diff --git a/interface/CMakeLists.txt b/interface/CMakeLists.txt
index 2fce668..086cc87 100644
--- a/interface/CMakeLists.txt
+++ b/interface/CMakeLists.txt
@@ -45,7 +45,7 @@
         $<$<BOOL:${TFM_NS_CLIENT_IDENTIFICATION}>:TFM_NS_CLIENT_IDENTIFICATION>
         $<$<BOOL:${CONFIG_TFM_ENABLE_CTX_MGMT}>:CONFIG_TFM_ENABLE_CTX_MGMT>
         $<$<BOOL:${TFM_ISOLATION_LEVEL}>:TFM_LVL=${TFM_ISOLATION_LEVEL}>
-        $<$<VERSION_GREATER:${TFM_ISOLATION_LEVEL},1>:CONFIG_TFM_ENABLE_MEMORY_PROTECT>
+        $<$<OR:$<VERSION_GREATER:${TFM_ISOLATION_LEVEL},1>,$<STREQUAL:"${TEST_PSA_API}","IPC">>:CONFIG_TFM_ENABLE_MEMORY_PROTECT>
         $<$<BOOL:${TFM_MULTI_CORE_TOPOLOGY}>:TFM_MULTI_CORE_TOPOLOGY>
         $<$<BOOL:${TFM_MULTI_CORE_MULTI_CLIENT_CALL}>:TFM_MULTI_CORE_MULTI_CLIENT_CALL>
 )