diff --git a/ChangeLog.d/remove-compat-2.x.txt b/ChangeLog.d/remove-compat-2.x.txt
new file mode 100644
index 0000000..37f012c
--- /dev/null
+++ b/ChangeLog.d/remove-compat-2.x.txt
@@ -0,0 +1,2 @@
+Removals
+   * Remove compat-2-x.h header from mbedtls.
diff --git a/include/mbedtls/compat-2.x.h b/include/mbedtls/compat-2.x.h
deleted file mode 100644
index 096341b..0000000
--- a/include/mbedtls/compat-2.x.h
+++ /dev/null
@@ -1,46 +0,0 @@
-/**
- * \file compat-2.x.h
- *
- * \brief Compatibility definitions
- *
- * \deprecated Use the new names directly instead
- */
-/*
- *  Copyright The Mbed TLS Contributors
- *  SPDX-License-Identifier: Apache-2.0 OR GPL-2.0-or-later
- */
-
-#if defined(MBEDTLS_DEPRECATED_WARNING)
-#warning "Including compat-2.x.h is deprecated"
-#endif
-
-#ifndef MBEDTLS_COMPAT2X_H
-#define MBEDTLS_COMPAT2X_H
-
-/*
- * Macros for renamed functions
- */
-#define mbedtls_ctr_drbg_update_ret   mbedtls_ctr_drbg_update
-#define mbedtls_hmac_drbg_update_ret  mbedtls_hmac_drbg_update
-#define mbedtls_md5_starts_ret        mbedtls_md5_starts
-#define mbedtls_md5_update_ret        mbedtls_md5_update
-#define mbedtls_md5_finish_ret        mbedtls_md5_finish
-#define mbedtls_md5_ret               mbedtls_md5
-#define mbedtls_ripemd160_starts_ret  mbedtls_ripemd160_starts
-#define mbedtls_ripemd160_update_ret  mbedtls_ripemd160_update
-#define mbedtls_ripemd160_finish_ret  mbedtls_ripemd160_finish
-#define mbedtls_ripemd160_ret         mbedtls_ripemd160
-#define mbedtls_sha1_starts_ret       mbedtls_sha1_starts
-#define mbedtls_sha1_update_ret       mbedtls_sha1_update
-#define mbedtls_sha1_finish_ret       mbedtls_sha1_finish
-#define mbedtls_sha1_ret              mbedtls_sha1
-#define mbedtls_sha256_starts_ret     mbedtls_sha256_starts
-#define mbedtls_sha256_update_ret     mbedtls_sha256_update
-#define mbedtls_sha256_finish_ret     mbedtls_sha256_finish
-#define mbedtls_sha256_ret            mbedtls_sha256
-#define mbedtls_sha512_starts_ret     mbedtls_sha512_starts
-#define mbedtls_sha512_update_ret     mbedtls_sha512_update
-#define mbedtls_sha512_finish_ret     mbedtls_sha512_finish
-#define mbedtls_sha512_ret            mbedtls_sha512
-
-#endif /* MBEDTLS_COMPAT2X_H */