diff --git a/configs/config-tfm.h b/configs/config-tfm.h
index 191e4c4..85b677b 100644
--- a/configs/config-tfm.h
+++ b/configs/config-tfm.h
@@ -21,16 +21,6 @@
 /* MBEDTLS_PSA_CRYPTO_SPM needs third-party files, so disable it. */
 #undef MBEDTLS_PSA_CRYPTO_SPM
 
-/* TF-M provides its own dummy implementations to save code size.
- * We don't have any way to disable the tests that need these feature,
- * so we just keep AES decryption enabled. We will resolve this through
- * an official way to disable AES decryption, then this deviation
- * will no longer be needed:
- * https://github.com/Mbed-TLS/mbedtls/issues/7368
- */
-#undef MBEDTLS_AES_SETKEY_DEC_ALT
-#undef MBEDTLS_AES_DECRYPT_ALT
-
 /* Use built-in platform entropy functions (TF-M provides its own). */
 #undef MBEDTLS_NO_PLATFORM_ENTROPY
 
@@ -38,3 +28,35 @@
  * but using the native allocator is faster and works better with
  * memory management analysis frameworks such as ASan. */
 #undef MBEDTLS_MEMORY_BUFFER_ALLOC_C
+
+// This macro is enabled in TFM Medium but is disabled here because it is
+// incompatible with baremetal builds in Mbed TLS.
+#undef MBEDTLS_PSA_CRYPTO_STORAGE_C
+
+// This macro is enabled in TFM Medium but is disabled here because it is
+// incompatible with baremetal builds in Mbed TLS.
+#undef MBEDTLS_ENTROPY_NV_SEED
+
+// These platform-related TF-M settings are not useful here.
+#undef MBEDTLS_PLATFORM_NO_STD_FUNCTIONS
+#undef MBEDTLS_PLATFORM_STD_MEM_HDR
+#undef MBEDTLS_PLATFORM_SNPRINTF_MACRO
+#undef MBEDTLS_PLATFORM_PRINTF_ALT
+#undef MBEDTLS_PLATFORM_STD_EXIT_SUCCESS
+#undef MBEDTLS_PLATFORM_STD_EXIT_FAILURE
+
+/*
+ * In order to get an example config that works cleanly out-of-the-box
+ * for both baremetal and non-baremetal builds, we detect baremetal builds
+ * and set this variable automatically.
+ */
+#if defined(__IAR_SYSTEMS_ICC__) || defined(__ARM_EABI__)
+#define MBEDTLS_NO_PLATFORM_ENTROPY
+#endif
+
+/***********************************************************************
+ * Local changes to crypto config below this delimiter
+ **********************************************************************/
+
+// We expect TF-M to pick this up soon
+#define MBEDTLS_BLOCK_CIPHER_NO_DECRYPT
diff --git a/configs/ext/crypto_config_profile_medium.h b/configs/ext/crypto_config_profile_medium.h
index 682835a..63ed470 100644
--- a/configs/ext/crypto_config_profile_medium.h
+++ b/configs/ext/crypto_config_profile_medium.h
@@ -50,7 +50,7 @@
 //#define PSA_WANT_ALG_CFB                        1
 //#define PSA_WANT_ALG_CHACHA20_POLY1305          1
 //#define PSA_WANT_ALG_CTR                        1
-#define PSA_WANT_ALG_DETERMINISTIC_ECDSA        1
+//#define PSA_WANT_ALG_DETERMINISTIC_ECDSA        1
 //#define PSA_WANT_ALG_ECB_NO_PADDING             1
 #define PSA_WANT_ALG_ECDH                       1
 #define PSA_WANT_ALG_ECDSA                      1
@@ -105,33 +105,27 @@
 //#define PSA_WANT_KEY_TYPE_CAMELLIA              1
 //#define PSA_WANT_KEY_TYPE_CHACHA20              1
 //#define PSA_WANT_KEY_TYPE_DES                   1
-#define PSA_WANT_KEY_TYPE_ECC_KEY_PAIR_BASIC    1
+//#define PSA_WANT_KEY_TYPE_ECC_KEY_PAIR          1 /* Deprecated */
+#define PSA_WANT_KEY_TYPE_ECC_PUBLIC_KEY        1
+#define PSA_WANT_KEY_TYPE_RAW_DATA              1
+//#define PSA_WANT_KEY_TYPE_RSA_KEY_PAIR          1 /* Deprecated */
+//#define PSA_WANT_KEY_TYPE_RSA_PUBLIC_KEY        1
+
+/*
+ * The following symbols extend and deprecate the legacy
+ * PSA_WANT_KEY_TYPE_xxx_KEY_PAIR ones. They include the usage of that key in
+ * the name's suffix. "_USE" is the most generic and it can be used to describe
+ * a generic suport, whereas other ones add more features on top of that and
+ * they are more specific.
+ */
+#define PSA_WANT_KEY_TYPE_ECC_KEY_PAIR_BASIC      1
 #define PSA_WANT_KEY_TYPE_ECC_KEY_PAIR_IMPORT   1
 #define PSA_WANT_KEY_TYPE_ECC_KEY_PAIR_EXPORT   1
 #define PSA_WANT_KEY_TYPE_ECC_KEY_PAIR_GENERATE 1
-#define PSA_WANT_KEY_TYPE_ECC_KEY_PAIR_DERIVE   1
-#define PSA_WANT_KEY_TYPE_ECC_PUBLIC_KEY        1
-#define PSA_WANT_KEY_TYPE_RAW_DATA              1
-//#define PSA_WANT_KEY_TYPE_RSA_KEY_PAIR          1
-//#define PSA_WANT_KEY_TYPE_RSA_PUBLIC_KEY        1
+//#define PSA_WANT_KEY_TYPE_ECC_KEY_PAIR_DERIVE   1
 
-/***********************************************************************
- * Local edits below this delimiter
- **********************************************************************/
-
-/* Between Mbed TLS 3.4 and 3.5, the PSA_WANT_KEY_TYPE_RSA_KEY_PAIR macro
- * (commented-out above) has been replaced with the following new macros: */
-//#define PSA_WANT_KEY_TYPE_RSA_KEY_PAIR_BASIC      1
-//#define PSA_WANT_KEY_TYPE_RSA_KEY_PAIR_IMPORT     1
-//#define PSA_WANT_KEY_TYPE_RSA_KEY_PAIR_EXPORT     1
-//#define PSA_WANT_KEY_TYPE_RSA_KEY_PAIR_GENERATE   1
-//#define PSA_WANT_KEY_TYPE_RSA_KEY_PAIR_DERIVE     1 /* Not supported */
-
-/* Between Mbed TLS 3.4 and 3.5, the following macros have been added: */
-//#define PSA_WANT_KEY_TYPE_DH_KEY_PAIR_BASIC       1
-//#define PSA_WANT_KEY_TYPE_DH_KEY_PAIR_IMPORT    1
-//#define PSA_WANT_KEY_TYPE_DH_KEY_PAIR_EXPORT    1
-//#define PSA_WANT_KEY_TYPE_DH_KEY_PAIR_GENERATE  1
-//#define PSA_WANT_KEY_TYPE_DH_KEY_PAIR_DERIVE    1 // Not supported
+#ifdef CRYPTO_HW_ACCELERATOR
+#include "crypto_accelerator_config.h"
+#endif
 
 #endif /* PROFILE_M_PSA_CRYPTO_CONFIG_H */
diff --git a/configs/ext/tfm_mbedcrypto_config_profile_medium.h b/configs/ext/tfm_mbedcrypto_config_profile_medium.h
index 53243dd..beebddf 100644
--- a/configs/ext/tfm_mbedcrypto_config_profile_medium.h
+++ b/configs/ext/tfm_mbedcrypto_config_profile_medium.h
@@ -15,6 +15,8 @@
 #ifndef PROFILE_M_MBEDTLS_CONFIG_H
 #define PROFILE_M_MBEDTLS_CONFIG_H
 
+//#include "config_tfm.h"
+
 #if defined(_MSC_VER) && !defined(_CRT_SECURE_NO_DEPRECATE)
 #define _CRT_SECURE_NO_DEPRECATE 1
 #endif
@@ -81,44 +83,6 @@
  */
 
 /**
- * \def MBEDTLS_MD2_PROCESS_ALT
- *
- * MBEDTLS__FUNCTION_NAME__ALT: Uncomment a macro to let mbed TLS use you
- * alternate core implementation of symmetric crypto or hash function. Keep in
- * mind that function prototypes should remain the same.
- *
- * This replaces only one function. The header file from mbed TLS is still
- * used, in contrast to the MBEDTLS__MODULE_NAME__ALT flags.
- *
- * Example: In case you uncomment MBEDTLS_SHA256_PROCESS_ALT, mbed TLS will
- * no longer provide the mbedtls_sha1_process() function, but it will still provide
- * the other function (using your mbedtls_sha1_process() function) and the definition
- * of mbedtls_sha1_context, so your implementation of mbedtls_sha1_process must be compatible
- * with this definition.
- *
- * \note Because of a signature change, the core AES encryption and decryption routines are
- *       currently named mbedtls_aes_internal_encrypt and mbedtls_aes_internal_decrypt,
- *       respectively. When setting up alternative implementations, these functions should
- *       be overridden, but the wrapper functions mbedtls_aes_decrypt and mbedtls_aes_encrypt
- *       must stay untouched.
- *
- * \note If you use the AES_xxx_ALT macros, then is is recommended to also set
- *       MBEDTLS_AES_ROM_TABLES in order to help the linker garbage-collect the AES
- *       tables.
- *
- * Uncomment a macro to enable alternate implementation of the corresponding
- * function.
- *
- * \warning   MD2, MD4, MD5, DES and SHA-1 are considered weak and their use
- *            constitutes a security risk. If possible, we recommend avoiding
- *            dependencies on them, and considering stronger message digests
- *            and ciphers instead.
- *
- */
-#define MBEDTLS_AES_SETKEY_DEC_ALT
-#define MBEDTLS_AES_DECRYPT_ALT
-
-/**
  * \def MBEDTLS_AES_ROM_TABLES
  *
  * Use precomputed AES tables stored in ROM.
@@ -172,21 +136,6 @@
 #define MBEDTLS_ECP_NIST_OPTIM
 
 /**
- * \def MBEDTLS_ERROR_STRERROR_DUMMY
- *
- * Enable a dummy error function to make use of mbedtls_strerror() in
- * third party libraries easier when MBEDTLS_ERROR_C is disabled
- * (no effect when MBEDTLS_ERROR_C is enabled).
- *
- * You can safely disable this if MBEDTLS_ERROR_C is enabled, or if you're
- * not using mbedtls_strerror() or error_strerror() in your application.
- *
- * Disable if you run into name conflicts and want to really remove the
- * mbedtls_strerror()
- */
-#define MBEDTLS_ERROR_STRERROR_DUMMY
-
-/**
  * \def MBEDTLS_NO_PLATFORM_ENTROPY
  *
  * Do not use built-in platform entropy functions.
@@ -223,26 +172,7 @@
  * \note The entropy collector will write to the seed file before entropy is
  *       given to an external source, to update it.
  */
-// This macro is enabled in TFM Medium but is disabled here because it is
-// incompatible with baremetal builds in Mbed TLS.
-//#define MBEDTLS_ENTROPY_NV_SEED
-
-/* MBEDTLS_PSA_CRYPTO_KEY_ID_ENCODES_OWNER
- *
- * Enable key identifiers that encode a key owner identifier.
- *
- * This is only meaningful when building the library as part of a
- * multi-client service. When you activate this option, you must provide an
- * implementation of the type mbedtls_key_owner_id_t and a translation from
- * mbedtls_svc_key_id_t to file name in all the storage backends that you
- * you wish to support.
- *
- * Note that while this define has been removed from TF-M's copy of this config
- * file, TF-M still passes this option to Mbed TLS during the build via CMake.
- * Therefore we keep it in our copy. See discussion on PR #7426 for more info.
- *
- */
-#define MBEDTLS_PSA_CRYPTO_KEY_ID_ENCODES_OWNER
+#define MBEDTLS_ENTROPY_NV_SEED
 
 /**
  * \def MBEDTLS_PSA_CRYPTO_SPM
@@ -326,26 +256,21 @@
 #define MBEDTLS_AES_C
 
 /**
- * \def MBEDTLS_BLOCK_CIPHER_NO_DECRYPT
+ * \def MBEDTLS_AES_ONLY_128_BIT_KEY_LENGTH
  *
- * Remove decryption operation for AES, ARIA and Camellia block cipher.
+ * Use only 128-bit keys in AES operations to save ROM.
  *
- * \note  This feature is incompatible with insecure block cipher,
- *        MBEDTLS_DES_C, and cipher modes which always require decryption
- *        operation, MBEDTLS_CIPHER_MODE_CBC, MBEDTLS_CIPHER_MODE_XTS and
- *        MBEDTLS_NIST_KW_C. When #MBEDTLS_PSA_CRYPTO_CONFIG is enabled,
- *        this feature is incompatible with following supported PSA equivalence,
- *        PSA_WANT_ALG_ECB_NO_PADDING, PSA_WANT_ALG_CBC_NO_PADDING,
- *        PSA_WANT_ALG_CBC_PKCS7 and PSA_WANT_KEY_TYPE_DES.
+ * Uncomment this macro to remove support for AES operations that use 192-
+ * or 256-bit keys.
+ *
+ * Uncommenting this macro reduces the size of AES code by ~300 bytes
+ * on v8-M/Thumb2.
  *
  * Module:  library/aes.c
- *          library/aesce.c
- *          library/aesni.c
- *          library/aria.c
- *          library/camellia.c
- *          library/cipher.c
+ *
+ * Requires: MBEDTLS_AES_C
  */
-#define MBEDTLS_BLOCK_CIPHER_NO_DECRYPT
+#define MBEDTLS_AES_ONLY_128_BIT_KEY_LENGTH
 
 /**
  * \def MBEDTLS_CIPHER_C
@@ -389,18 +314,6 @@
 #define MBEDTLS_ENTROPY_C
 
 /**
- * \def MBEDTLS_ERROR_C
- *
- * Enable error code to error string conversion.
- *
- * Module:  library/error.c
- * Caller:
- *
- * This module enables mbedtls_strerror().
- */
-#define MBEDTLS_ERROR_C
-
-/**
  * \def MBEDTLS_HKDF_C
  *
  * Enable the HKDF algorithm (RFC 5869).
@@ -413,40 +326,7 @@
  * This module adds support for the Hashed Message Authentication Code
  * (HMAC)-based key derivation function (HKDF).
  */
-#define MBEDTLS_HKDF_C /* Used for HUK deriviation */
-
-/**
- * \def MBEDTLS_MD_C
- *
- * Enable the generic layer for message digest (hashing) and HMAC.
- *
- * Requires: one of: MBEDTLS_MD5_C, MBEDTLS_RIPEMD160_C, MBEDTLS_SHA1_C,
- *                   MBEDTLS_SHA224_C, MBEDTLS_SHA256_C, MBEDTLS_SHA384_C,
- *                   MBEDTLS_SHA512_C, or MBEDTLS_PSA_CRYPTO_C with at least
- *                   one hash.
- * Module:  library/md.c
- * Caller:  library/constant_time.c
- *          library/ecdsa.c
- *          library/ecjpake.c
- *          library/hkdf.c
- *          library/hmac_drbg.c
- *          library/pk.c
- *          library/pkcs5.c
- *          library/pkcs12.c
- *          library/psa_crypto_ecp.c
- *          library/psa_crypto_rsa.c
- *          library/rsa.c
- *          library/ssl_cookie.c
- *          library/ssl_msg.c
- *          library/ssl_tls.c
- *          library/x509.c
- *          library/x509_crt.c
- *          library/x509write_crt.c
- *          library/x509write_csr.c
- *
- * Uncomment to enable generic message digest wrappers.
- */
-#define MBEDTLS_MD_C
+//#define MBEDTLS_HKDF_C /* Used for HUK deriviation */
 
 /**
  * \def MBEDTLS_MEMORY_BUFFER_ALLOC_C
@@ -484,6 +364,15 @@
  */
 #define MBEDTLS_PLATFORM_C
 
+#define MBEDTLS_PLATFORM_NO_STD_FUNCTIONS
+#define MBEDTLS_PLATFORM_STD_MEM_HDR   <stdlib.h>
+
+#include <stdio.h>
+
+#define MBEDTLS_PLATFORM_SNPRINTF_MACRO      snprintf
+#define MBEDTLS_PLATFORM_PRINTF_ALT
+#define MBEDTLS_PLATFORM_STD_EXIT_SUCCESS  EXIT_SUCCESS
+#define MBEDTLS_PLATFORM_STD_EXIT_FAILURE  EXIT_FAILURE
 
 /**
  * \def MBEDTLS_PSA_CRYPTO_C
@@ -508,9 +397,7 @@
  *           either MBEDTLS_PSA_ITS_FILE_C or a native implementation of
  *           the PSA ITS interface
  */
-// This macro is enabled in TFM Medium but is disabled here because it is
-// incompatible with baremetal builds in Mbed TLS.
-//#define MBEDTLS_PSA_CRYPTO_STORAGE_C
+#define MBEDTLS_PSA_CRYPTO_STORAGE_C
 
 /* \} name SECTION: mbed TLS modules */
 
@@ -614,6 +501,47 @@
 /* ECP options */
 #define MBEDTLS_ECP_FIXED_POINT_OPTIM        0 /**< Disable fixed-point speed-up */
 
+/**
+ * Uncomment to enable p256-m. This is an alternative implementation of
+ * key generation, ECDH and (randomized) ECDSA on the curve SECP256R1.
+ * Compared to the default implementation:
+ *
+ * - p256-m has a much smaller code size and RAM footprint.
+ * - p256-m is only available via the PSA API. This includes the pk module
+ *   when #MBEDTLS_USE_PSA_CRYPTO is enabled.
+ * - p256-m does not support deterministic ECDSA, EC-JPAKE, custom protocols
+ *   over the core arithmetic, or deterministic derivation of keys.
+ *
+ * We recommend enabling this option if your application uses the PSA API
+ * and the only elliptic curve support it needs is ECDH and ECDSA over
+ * SECP256R1.
+ *
+ * If you enable this option, you do not need to enable any ECC-related
+ * MBEDTLS_xxx option. You do need to separately request support for the
+ * cryptographic mechanisms through the PSA API:
+ * - #MBEDTLS_PSA_CRYPTO_C and #MBEDTLS_PSA_CRYPTO_CONFIG for PSA-based
+ *   configuration;
+ * - #MBEDTLS_USE_PSA_CRYPTO if you want to use p256-m from PK, X.509 or TLS;
+ * - #PSA_WANT_ECC_SECP_R1_256;
+ * - #PSA_WANT_ALG_ECDH and/or #PSA_WANT_ALG_ECDSA as needed;
+ * - #PSA_WANT_KEY_TYPE_ECC_PUBLIC_KEY, #PSA_WANT_KEY_TYPE_ECC_KEY_PAIR_BASIC,
+ *   #PSA_WANT_KEY_TYPE_ECC_KEY_PAIR_IMPORT,
+ *   #PSA_WANT_KEY_TYPE_ECC_KEY_PAIR_EXPORT and/or
+ *   #PSA_WANT_KEY_TYPE_ECC_KEY_PAIR_GENERATE as needed.
+ *
+ * \note To benefit from the smaller code size of p256-m, make sure that you
+ *       do not enable any ECC-related option not supported by p256-m: this
+ *       would cause the built-in ECC implementation to be built as well, in
+ *       order to provide the required option.
+ *       Make sure #PSA_WANT_ALG_DETERMINISTIC_ECDSA, #PSA_WANT_ALG_JPAKE and
+ *       #PSA_WANT_KEY_TYPE_ECC_KEY_PAIR_DERIVE, and curves other than
+ *       SECP256R1 are disabled as they are not supported by this driver.
+ *       Also, avoid defining #MBEDTLS_PK_PARSE_EC_COMPRESSED or
+ *       #MBEDTLS_PK_PARSE_EC_EXTENDED as those currently require a subset of
+ *       the built-in ECC implementation, see docs/driver-only-builds.md.
+ */
+#define MBEDTLS_PSA_P256M_DRIVER_ENABLED
+
 /* \} name SECTION: Customisation configuration options */
 
 #if CRYPTO_NV_SEED
@@ -621,7 +549,7 @@
 #endif /* CRYPTO_NV_SEED */
 
 #if !defined(CRYPTO_HW_ACCELERATOR) && defined(MBEDTLS_ENTROPY_NV_SEED)
-#include "mbedtls_entropy_nv_seed_config.h"
+//#include "mbedtls_entropy_nv_seed_config.h"
 #endif
 
 #ifdef CRYPTO_HW_ACCELERATOR
diff --git a/include/mbedtls/check_config.h b/include/mbedtls/check_config.h
index 792e7d7..9b5b646 100644
--- a/include/mbedtls/check_config.h
+++ b/include/mbedtls/check_config.h
@@ -785,9 +785,8 @@
 #error "MBEDTLS_PSA_CRYPTO_C defined, but not all prerequisites (missing RNG)"
 #endif
 
-#if defined(MBEDTLS_PSA_CRYPTO_C) && \
-    (defined(PSA_HAVE_SOFT_BLOCK_CIPHER) || defined(PSA_HAVE_SOFT_BLOCK_AEAD)) && \
-    !defined(MBEDTLS_CIPHER_C)
+#if defined(MBEDTLS_PSA_CRYPTO_C) && defined(PSA_HAVE_SOFT_BLOCK_MODE) && \
+    defined(PSA_HAVE_SOFT_BLOCK_CIPHER) && !defined(MBEDTLS_CIPHER_C)
 #error "MBEDTLS_PSA_CRYPTO_C defined, but not all prerequisites"
 #endif
 
diff --git a/include/mbedtls/config_adjust_psa_from_legacy.h b/include/mbedtls/config_adjust_psa_from_legacy.h
index 60b00c1..b841875 100644
--- a/include/mbedtls/config_adjust_psa_from_legacy.h
+++ b/include/mbedtls/config_adjust_psa_from_legacy.h
@@ -25,9 +25,11 @@
 
 #if defined(MBEDTLS_CCM_C)
 #define MBEDTLS_PSA_BUILTIN_ALG_CCM 1
-#define MBEDTLS_PSA_BUILTIN_ALG_CCM_STAR_NO_TAG 1
 #define PSA_WANT_ALG_CCM 1
+#if defined(MBEDTLS_CIPHER_C)
+#define MBEDTLS_PSA_BUILTIN_ALG_CCM_STAR_NO_TAG 1
 #define PSA_WANT_ALG_CCM_STAR_NO_TAG 1
+#endif /* MBEDTLS_CIPHER_C */
 #endif /* MBEDTLS_CCM_C */
 
 #if defined(MBEDTLS_CMAC_C)
@@ -247,8 +249,9 @@
 #endif
 #endif
 
-#if defined(MBEDTLS_AES_C) || defined(MBEDTLS_DES_C) || \
-    defined(MBEDTLS_ARIA_C) || defined(MBEDTLS_CAMELLIA_C)
+#if (defined(MBEDTLS_AES_C) || defined(MBEDTLS_DES_C) || \
+    defined(MBEDTLS_ARIA_C) || defined(MBEDTLS_CAMELLIA_C)) && \
+    defined(MBEDTLS_CIPHER_C)
 #define MBEDTLS_PSA_BUILTIN_ALG_ECB_NO_PADDING 1
 #define PSA_WANT_ALG_ECB_NO_PADDING 1
 #endif
diff --git a/include/mbedtls/threading.h b/include/mbedtls/threading.h
index ed16a23..b504233 100644
--- a/include/mbedtls/threading.h
+++ b/include/mbedtls/threading.h
@@ -28,10 +28,14 @@
 #include <pthread.h>
 typedef struct mbedtls_threading_mutex_t {
     pthread_mutex_t MBEDTLS_PRIVATE(mutex);
-    /* is_valid is 0 after a failed init or a free, and nonzero after a
-     * successful init. This field is not considered part of the public
-     * API of Mbed TLS and may change without notice. */
-    char MBEDTLS_PRIVATE(is_valid);
+
+    /* WARNING - state should only be accessed when holding the mutex lock in
+     * tests/src/threading_helpers.c, otherwise corruption can occur.
+     * state will be 0 after a failed init or a free, and nonzero after a
+     * successful init. This field is for testing only and thus not considered
+     * part of the public API of Mbed TLS and may change without notice.*/
+    char MBEDTLS_PRIVATE(state);
+
 } mbedtls_threading_mutex_t;
 #endif
 
diff --git a/library/common.h b/library/common.h
index c20f6b2..bd5a0c3 100644
--- a/library/common.h
+++ b/library/common.h
@@ -23,6 +23,15 @@
 #include <arm_neon.h>
 #endif /* __ARM_NEON */
 
+
+#if defined(__GNUC__) && !defined(__ARMCC_VERSION) && !defined(__clang__) \
+    && !defined(__llvm__) && !defined(__INTEL_COMPILER)
+/* Defined if the compiler really is gcc and not clang, etc */
+#define MBEDTLS_COMPILER_IS_GCC
+#define MBEDTLS_GCC_VERSION \
+    (__GNUC__ * 10000 + __GNUC_MINOR__ * 100 + __GNUC_PATCHLEVEL__)
+#endif
+
 /** Helper to define a function as static except when building invasive tests.
  *
  * If a function is only used inside its own source file and should be
@@ -169,7 +178,9 @@
 {
     size_t i = 0;
 #if defined(MBEDTLS_EFFICIENT_UNALIGNED_ACCESS)
-#if defined(__ARM_NEON)
+#if defined(__ARM_NEON) && \
+    (!defined(MBEDTLS_COMPILER_IS_GCC) || \
+    (defined(MBEDTLS_COMPILER_IS_GCC) && MBEDTLS_GCC_VERSION >= 70300))
     for (; (i + 16) <= n; i += 16) {
         uint8x16_t v1 = vld1q_u8(a + i);
         uint8x16_t v2 = vld1q_u8(b + i);
@@ -324,12 +335,6 @@
 #define MBEDTLS_ASSUME(x)       do { } while (0)
 #endif
 
-#if defined(__GNUC__) && !defined(__ARMCC_VERSION) && !defined(__clang__) \
-    && !defined(__llvm__) && !defined(__INTEL_COMPILER)
-/* Defined if the compiler really is gcc and not clang, etc */
-#define MBEDTLS_COMPILER_IS_GCC
-#endif
-
 /* For gcc -Os, override with -O2 for a given function.
  *
  * This will not affect behaviour for other optimisation settings, e.g. -O0.
diff --git a/library/threading.c b/library/threading.c
index 52fe8fc..873b507 100644
--- a/library/threading.c
+++ b/library/threading.c
@@ -56,28 +56,27 @@
         return;
     }
 
-    /* A nonzero value of is_valid indicates a successfully initialized
-     * mutex. This is a workaround for not being able to return an error
-     * code for this function. The lock/unlock functions return an error
-     * if is_valid is nonzero. The Mbed TLS unit test code uses this field
-     * to distinguish more states of the mutex; see
-     * tests/src/threading_helpers for details. */
-    mutex->is_valid = pthread_mutex_init(&mutex->mutex, NULL) == 0;
+    /* One problem here is that calling lock on a pthread mutex without first
+     * having initialised it is undefined behaviour. Obviously we cannot check
+     * this here in a thread safe manner without a significant performance
+     * hit, so state transitions are checked in tests only via the state
+     * variable. Please make sure any new mutex that gets added is exercised in
+     * tests; see tests/src/threading_helpers.c for more details. */
+    (void) pthread_mutex_init(&mutex->mutex, NULL);
 }
 
 static void threading_mutex_free_pthread(mbedtls_threading_mutex_t *mutex)
 {
-    if (mutex == NULL || !mutex->is_valid) {
+    if (mutex == NULL) {
         return;
     }
 
     (void) pthread_mutex_destroy(&mutex->mutex);
-    mutex->is_valid = 0;
 }
 
 static int threading_mutex_lock_pthread(mbedtls_threading_mutex_t *mutex)
 {
-    if (mutex == NULL || !mutex->is_valid) {
+    if (mutex == NULL) {
         return MBEDTLS_ERR_THREADING_BAD_INPUT_DATA;
     }
 
@@ -90,7 +89,7 @@
 
 static int threading_mutex_unlock_pthread(mbedtls_threading_mutex_t *mutex)
 {
-    if (mutex == NULL || !mutex->is_valid) {
+    if (mutex == NULL) {
         return MBEDTLS_ERR_THREADING_BAD_INPUT_DATA;
     }
 
diff --git a/programs/ssl/ssl_test_lib.c b/programs/ssl/ssl_test_lib.c
index 6e0c615..b49dd67 100644
--- a/programs/ssl/ssl_test_lib.c
+++ b/programs/ssl/ssl_test_lib.c
@@ -435,6 +435,9 @@
 
 void test_hooks_free(void)
 {
+#if defined(MBEDTLS_TEST_MUTEX_USAGE)
+    mbedtls_test_mutex_usage_end();
+#endif
 }
 
 #endif /* MBEDTLS_TEST_HOOKS */
diff --git a/tests/include/test/helpers.h b/tests/include/test/helpers.h
index ba117fb..7c962a2 100644
--- a/tests/include/test/helpers.h
+++ b/tests/include/test/helpers.h
@@ -20,6 +20,21 @@
 
 #include "mbedtls/build_info.h"
 
+#if defined(__SANITIZE_ADDRESS__) /* gcc -fsanitize=address */
+#  define MBEDTLS_TEST_HAVE_ASAN
+#endif
+#if defined(__has_feature)
+#  if __has_feature(address_sanitizer) /* clang -fsanitize=address */
+#    define MBEDTLS_TEST_HAVE_ASAN
+#  endif
+#  if __has_feature(memory_sanitizer) /* clang -fsanitize=memory */
+#    define MBEDTLS_TEST_HAVE_MSAN
+#  endif
+#  if __has_feature(thread_sanitizer) /* clang -fsanitize=thread */
+#    define MBEDTLS_TEST_HAVE_TSAN
+#  endif
+#endif
+
 #if defined(MBEDTLS_THREADING_C) && defined(MBEDTLS_THREADING_PTHREAD) && \
     defined(MBEDTLS_TEST_HOOKS)
 #define MBEDTLS_TEST_MUTEX_USAGE
@@ -240,10 +255,18 @@
 #endif
 
 #if defined(MBEDTLS_TEST_MUTEX_USAGE)
-/** Permanently activate the mutex usage verification framework. See
- * threading_helpers.c for information. */
+/**
+ *  Activate the mutex usage verification framework. See threading_helpers.c for
+ *  information.
+ *  */
 void mbedtls_test_mutex_usage_init(void);
 
+/**
+ *  Deactivate the mutex usage verification framework. See threading_helpers.c
+ *  for information.
+ */
+void mbedtls_test_mutex_usage_end(void);
+
 /** Call this function after executing a test case to check for mutex usage
  * errors. */
 void mbedtls_test_mutex_usage_check(void);
diff --git a/tests/scripts/all.sh b/tests/scripts/all.sh
index 08136c0..462597b 100755
--- a/tests/scripts/all.sh
+++ b/tests/scripts/all.sh
@@ -1583,9 +1583,7 @@
         # on CIPHER_C so we disable them.
         # This does not hold for KEY_TYPE_CHACHA20 and ALG_CHACHA20_POLY1305
         # so we keep them enabled.
-        scripts/config.py -f $CRYPTO_CONFIG_H unset PSA_WANT_ALG_CCM
         scripts/config.py -f $CRYPTO_CONFIG_H unset PSA_WANT_ALG_CCM_STAR_NO_TAG
-        scripts/config.py -f $CRYPTO_CONFIG_H unset PSA_WANT_ALG_GCM
         scripts/config.py -f $CRYPTO_CONFIG_H unset PSA_WANT_ALG_CMAC
         scripts/config.py -f $CRYPTO_CONFIG_H unset PSA_WANT_ALG_CBC_NO_PADDING
         scripts/config.py -f $CRYPTO_CONFIG_H unset PSA_WANT_ALG_CBC_PKCS7
@@ -1594,27 +1592,19 @@
         scripts/config.py -f $CRYPTO_CONFIG_H unset PSA_WANT_ALG_ECB_NO_PADDING
         scripts/config.py -f $CRYPTO_CONFIG_H unset PSA_WANT_ALG_OFB
         scripts/config.py -f $CRYPTO_CONFIG_H unset PSA_WANT_ALG_STREAM_CIPHER
-        scripts/config.py -f $CRYPTO_CONFIG_H unset PSA_WANT_KEY_TYPE_AES
         scripts/config.py -f $CRYPTO_CONFIG_H unset PSA_WANT_KEY_TYPE_DES
-        scripts/config.py -f $CRYPTO_CONFIG_H unset PSA_WANT_KEY_TYPE_CAMELLIA
-        scripts/config.py -f $CRYPTO_CONFIG_H unset PSA_WANT_KEY_TYPE_ARIA
     else
         # Don't pull in cipher via PSA mechanisms
         scripts/config.py unset MBEDTLS_PSA_CRYPTO_CONFIG
         # Disable cipher modes/keys that make PSA depend on CIPHER_C.
         # Keep CHACHA20 and CHACHAPOLY enabled since they do not depend on CIPHER_C.
         scripts/config.py unset-all MBEDTLS_CIPHER_MODE
-        scripts/config.py unset MBEDTLS_AES_C
         scripts/config.py unset MBEDTLS_DES_C
-        scripts/config.py unset MBEDTLS_ARIA_C
-        scripts/config.py unset MBEDTLS_CAMELLIA_C
         # Dependencies on AES_C
         scripts/config.py unset MBEDTLS_CTR_DRBG_C
     fi
     # The following modules directly depends on CIPHER_C
-    scripts/config.py unset MBEDTLS_CCM_C
     scripts/config.py unset MBEDTLS_CMAC_C
-    scripts/config.py unset MBEDTLS_GCM_C
     scripts/config.py unset MBEDTLS_NIST_KW_C
     scripts/config.py unset MBEDTLS_PKCS12_C
     scripts/config.py unset MBEDTLS_PKCS5_C
@@ -3251,14 +3241,6 @@
     #
     # Enable filesystem I/O for the benefit of PK parse/write tests.
     echo "#define MBEDTLS_FS_IO" >> "$CONFIG_H"
-
-    # Config adjustments for features that are not supported
-    # when using only drivers / by p256-m
-    #
-    # Disable all the features that auto-enable ECP_LIGHT (see config_adjust_legacy_crypto.h)
-    scripts/config.py -f "$CRYPTO_CONFIG_H" unset PSA_WANT_KEY_TYPE_ECC_KEY_PAIR_DERIVE
-    # Disable deterministic ECDSA as p256-m only does randomized
-    scripts/config.py -f "$CRYPTO_CONFIG_H" unset PSA_WANT_ALG_DETERMINISTIC_ECDSA
 }
 
 # Keep this in sync with component_test_tfm_config() as they are both meant
@@ -3268,8 +3250,8 @@
 
     common_tfm_config
 
-    # Build crypto library specifying we want to use P256M code for EC operations
-    make CFLAGS="$ASAN_CFLAGS -DMBEDTLS_PSA_P256M_DRIVER_ENABLED -I../tests/include/spe" LDFLAGS="$ASAN_CFLAGS"
+    # Build crypto library
+    make CFLAGS="$ASAN_CFLAGS -I../tests/include/spe" LDFLAGS="$ASAN_CFLAGS"
 
     # Make sure any built-in EC alg was not re-enabled by accident (additive config)
     not grep mbedtls_ecdsa_ library/ecdsa.o
@@ -3280,6 +3262,8 @@
     not grep mbedtls_rsa_ library/rsa.o
     not grep mbedtls_dhm_ library/dhm.o
     not grep mbedtls_mpi_ library/bignum.o
+    # Check that p256m was built
+    grep -q p256_ecdsa_ library/libmbedcrypto.a
 
     # Run the tests
     msg "test: TF-M config + p256m driver + accel ECDH(E)/ECDSA"
@@ -3292,9 +3276,16 @@
 component_test_tfm_config() {
     common_tfm_config
 
+    # Disable P256M driver, which is on by default, so that analyze_outcomes
+    # can compare this test with test_tfm_config_p256m_driver_accel_ec
+    echo "#undef MBEDTLS_PSA_P256M_DRIVER_ENABLED" >> "$CONFIG_H"
+
     msg "build: TF-M config"
     make CFLAGS='-Werror -Wall -Wextra -I../tests/include/spe' tests
 
+    # Check that p256m was not built
+    not grep p256_ecdsa_ library/libmbedcrypto.a
+
     msg "test: TF-M config"
     make test
 }
@@ -4119,8 +4110,7 @@
 
 component_build_tfm_armcc() {
     # test the TF-M configuration can build cleanly with various warning flags enabled
-    cp configs/ext/tfm_mbedcrypto_config_profile_medium.h "$CONFIG_H"
-    cp configs/ext/crypto_config_profile_medium.h "$CRYPTO_CONFIG_H"
+    cp configs/config-tfm.h "$CONFIG_H"
 
     msg "build: TF-M config, armclang armv7-m thumb2"
     armc6_build_test "--target=arm-arm-none-eabi -march=armv7-m -mthumb -Os -std=c99 -Werror -Wall -Wextra -Wwrite-strings -Wpointer-arith -Wimplicit-fallthrough -Wshadow -Wvla -Wformat=2 -Wno-format-nonliteral -Wshadow -Wasm-operand-widths -Wunused -I../tests/include/spe"
@@ -4132,8 +4122,7 @@
     # TF-M configuration needs a TF-M platform. A tweaked version of
     # the configuration that works on mainstream platforms is in
     # configs/config-tfm.h, tested via test-ref-configs.pl.
-    cp configs/ext/tfm_mbedcrypto_config_profile_medium.h "$CONFIG_H"
-    cp configs/ext/crypto_config_profile_medium.h "$CRYPTO_CONFIG_H"
+    cp configs/config-tfm.h "$CONFIG_H"
 
     msg "build: TF-M config, clang, armv7-m thumb2"
     make lib CC="clang" CFLAGS="--target=arm-linux-gnueabihf -march=armv7-m -mthumb -Os -std=c99 -Werror -Wall -Wextra -Wwrite-strings -Wpointer-arith -Wimplicit-fallthrough -Wshadow -Wvla -Wformat=2 -Wno-format-nonliteral -Wshadow -Wasm-operand-widths -Wunused -I../tests/include/spe"
diff --git a/tests/scripts/analyze_outcomes.py b/tests/scripts/analyze_outcomes.py
index a070b01..ca349d3 100755
--- a/tests/scripts/analyze_outcomes.py
+++ b/tests/scripts/analyze_outcomes.py
@@ -12,9 +12,36 @@
 import re
 import subprocess
 import os
+import typing
 
 import check_test_cases
 
+
+# `ComponentOutcomes` is a named tuple which is defined as:
+# ComponentOutcomes(
+#     successes = {
+#         "<suite_case>",
+#         ...
+#     },
+#     failures = {
+#         "<suite_case>",
+#         ...
+#     }
+# )
+# suite_case = "<suite>;<case>"
+ComponentOutcomes = typing.NamedTuple('ComponentOutcomes',
+                                      [('successes', typing.Set[str]),
+                                       ('failures', typing.Set[str])])
+
+# `Outcomes` is a representation of the outcomes file,
+# which defined as:
+# Outcomes = {
+#     "<component>": ComponentOutcomes,
+#     ...
+# }
+Outcomes = typing.Dict[str, ComponentOutcomes]
+
+
 class Results:
     """Process analysis results."""
 
@@ -40,35 +67,12 @@
     def _print_line(fmt, *args, **kwargs):
         sys.stderr.write((fmt + '\n').format(*args, **kwargs))
 
-class TestCaseOutcomes:
-    """The outcomes of one test case across many configurations."""
-    # pylint: disable=too-few-public-methods
-
-    def __init__(self):
-        # Collect a list of witnesses of the test case succeeding or failing.
-        # Currently we don't do anything with witnesses except count them.
-        # The format of a witness is determined by the read_outcome_file
-        # function; it's the platform and configuration joined by ';'.
-        self.successes = []
-        self.failures = []
-
-    def hits(self):
-        """Return the number of times a test case has been run.
-
-        This includes passes and failures, but not skips.
-        """
-        return len(self.successes) + len(self.failures)
-
-def execute_reference_driver_tests(results: Results, ref_component, driver_component, \
-                                   outcome_file):
+def execute_reference_driver_tests(results: Results, ref_component: str, driver_component: str, \
+                                   outcome_file: str) -> None:
     """Run the tests specified in ref_component and driver_component. Results
     are stored in the output_file and they will be used for the following
     coverage analysis"""
-    # If the outcome file already exists, we assume that the user wants to
-    # perform the comparison analysis again without repeating the tests.
-    if os.path.exists(outcome_file):
-        results.info("Outcome file ({}) already exists. Tests will be skipped.", outcome_file)
-        return
+    results.new_section("Test {} and {}", ref_component, driver_component)
 
     shell_command = "tests/scripts/all.sh --outcome-file " + outcome_file + \
                     " " + ref_component + " " + driver_component
@@ -78,24 +82,28 @@
     if ret_val != 0:
         results.error("failed to run reference/driver components")
 
-def analyze_coverage(results, outcomes, allow_list, full_coverage):
+def analyze_coverage(results: Results, outcomes: Outcomes,
+                     allow_list: typing.List[str], full_coverage: bool) -> None:
     """Check that all available test cases are executed at least once."""
     available = check_test_cases.collect_available_test_cases()
-    for key in available:
-        hits = outcomes[key].hits() if key in outcomes else 0
-        if hits == 0 and key not in allow_list:
+    for suite_case in available:
+        hit = any(suite_case in comp_outcomes.successes or
+                  suite_case in comp_outcomes.failures
+                  for comp_outcomes in outcomes.values())
+
+        if not hit and suite_case not in allow_list:
             if full_coverage:
-                results.error('Test case not executed: {}', key)
+                results.error('Test case not executed: {}', suite_case)
             else:
-                results.warning('Test case not executed: {}', key)
-        elif hits != 0 and key in allow_list:
+                results.warning('Test case not executed: {}', suite_case)
+        elif hit and suite_case in allow_list:
             # Test Case should be removed from the allow list.
             if full_coverage:
-                results.error('Allow listed test case was executed: {}', key)
+                results.error('Allow listed test case was executed: {}', suite_case)
             else:
-                results.warning('Allow listed test case was executed: {}', key)
+                results.warning('Allow listed test case was executed: {}', suite_case)
 
-def name_matches_pattern(name, str_or_re):
+def name_matches_pattern(name: str, str_or_re) -> bool:
     """Check if name matches a pattern, that may be a string or regex.
     - If the pattern is a string, name must be equal to match.
     - If the pattern is a regex, name must fully match.
@@ -103,24 +111,34 @@
     # The CI's python is too old for re.Pattern
     #if isinstance(str_or_re, re.Pattern):
     if not isinstance(str_or_re, str):
-        return str_or_re.fullmatch(name)
+        return str_or_re.fullmatch(name) is not None
     else:
         return str_or_re == name
 
-def analyze_driver_vs_reference(results: Results, outcomes,
-                                component_ref, component_driver,
-                                ignored_suites, ignored_tests=None):
-    """Check that all tests executed in the reference component are also
-    executed in the corresponding driver component.
+def analyze_driver_vs_reference(results: Results, outcomes: Outcomes,
+                                component_ref: str, component_driver: str,
+                                ignored_suites: typing.List[str], ignored_tests=None) -> None:
+    """Check that all tests passing in the reference component are also
+    passing in the corresponding driver component.
     Skip:
     - full test suites provided in ignored_suites list
     - only some specific test inside a test suite, for which the corresponding
       output string is provided
     """
-    seen_reference_passing = False
-    for key in outcomes:
-        # key is like "test_suite_foo.bar;Description of test case"
-        (full_test_suite, test_string) = key.split(';')
+    ref_outcomes = outcomes.get("component_" + component_ref)
+    driver_outcomes = outcomes.get("component_" + component_driver)
+
+    if ref_outcomes is None or driver_outcomes is None:
+        results.error("required components are missing: bad outcome file?")
+        return
+
+    if not ref_outcomes.successes:
+        results.error("no passing test in reference component: bad outcome file?")
+        return
+
+    for suite_case in ref_outcomes.successes:
+        # suite_case is like "test_suite_foo.bar;Description of test case"
+        (full_test_suite, test_string) = suite_case.split(';')
         test_suite = full_test_suite.split('.')[0] # retrieve main part of test suite name
 
         # Immediately skip fully-ignored test suites
@@ -136,67 +154,48 @@
                 if name_matches_pattern(test_string, str_or_re):
                     ignored = True
 
-        # Search for tests that run in reference component and not in driver component
-        driver_test_passed = False
-        reference_test_passed = False
-        for entry in outcomes[key].successes:
-            if component_driver in entry:
-                driver_test_passed = True
-            if component_ref in entry:
-                reference_test_passed = True
-                seen_reference_passing = True
-        if reference_test_passed and not driver_test_passed and not ignored:
-            results.error("PASS -> SKIP/FAIL: {}", key)
-        if ignored and driver_test_passed:
-            results.error("uselessly ignored: {}", key)
+        if not ignored and not suite_case in driver_outcomes.successes:
+            results.error("PASS -> SKIP/FAIL: {}", suite_case)
+        if ignored and suite_case in driver_outcomes.successes:
+            results.error("uselessly ignored: {}", suite_case)
 
-    if not seen_reference_passing:
-        results.error("no passing test in reference component: bad outcome file?")
-
-def analyze_outcomes(results: Results, outcomes, args):
+def analyze_outcomes(results: Results, outcomes: Outcomes, args) -> None:
     """Run all analyses on the given outcome collection."""
     analyze_coverage(results, outcomes, args['allow_list'],
                      args['full_coverage'])
 
-def read_outcome_file(outcome_file):
+def read_outcome_file(outcome_file: str) -> Outcomes:
     """Parse an outcome file and return an outcome collection.
-
-An outcome collection is a dictionary mapping keys to TestCaseOutcomes objects.
-The keys are the test suite name and the test case description, separated
-by a semicolon.
-"""
+    """
     outcomes = {}
     with open(outcome_file, 'r', encoding='utf-8') as input_file:
         for line in input_file:
-            (platform, config, suite, case, result, _cause) = line.split(';')
-            key = ';'.join([suite, case])
-            setup = ';'.join([platform, config])
-            if key not in outcomes:
-                outcomes[key] = TestCaseOutcomes()
+            (_platform, component, suite, case, result, _cause) = line.split(';')
+            # Note that `component` is not unique. If a test case passes on Linux
+            # and fails on FreeBSD, it'll end up in both the successes set and
+            # the failures set.
+            suite_case = ';'.join([suite, case])
+            if component not in outcomes:
+                outcomes[component] = ComponentOutcomes(set(), set())
             if result == 'PASS':
-                outcomes[key].successes.append(setup)
+                outcomes[component].successes.add(suite_case)
             elif result == 'FAIL':
-                outcomes[key].failures.append(setup)
+                outcomes[component].failures.add(suite_case)
+
     return outcomes
 
-def do_analyze_coverage(results: Results, outcome_file, args):
+def do_analyze_coverage(results: Results, outcomes: Outcomes, args) -> None:
     """Perform coverage analysis."""
     results.new_section("Analyze coverage")
-    outcomes = read_outcome_file(outcome_file)
     analyze_outcomes(results, outcomes, args)
 
-def do_analyze_driver_vs_reference(results: Results, outcome_file, args):
+def do_analyze_driver_vs_reference(results: Results, outcomes: Outcomes, args) -> None:
     """Perform driver vs reference analyze."""
     results.new_section("Analyze driver {} vs reference {}",
                         args['component_driver'], args['component_ref'])
 
-    execute_reference_driver_tests(results, args['component_ref'], \
-                                   args['component_driver'], outcome_file)
-
     ignored_suites = ['test_suite_' + x for x in args['ignored_suites']]
 
-    outcomes = read_outcome_file(outcome_file)
-
     analyze_driver_vs_reference(results, outcomes,
                                 args['component_ref'], args['component_driver'],
                                 ignored_suites, args['ignored_tests'])
@@ -232,6 +231,12 @@
                 'psa_crypto_low_hash.generated', # testing the builtins
             ],
             'ignored_tests': {
+                'test_suite_platform': [
+                    # Incompatible with sanitizers (e.g. ASan). If the driver
+                    # component uses a sanitizer but the reference component
+                    # doesn't, we have a PASS vs SKIP mismatch.
+                    'Check mbedtls_calloc overallocation',
+                ],
             }
         }
     },
@@ -255,6 +260,12 @@
                 'test_suite_pem': [
                     re.compile(r'PEM read .*(AES|DES|\bencrypt).*'),
                 ],
+                'test_suite_platform': [
+                    # Incompatible with sanitizers (e.g. ASan). If the driver
+                    # component uses a sanitizer but the reference component
+                    # doesn't, we have a PASS vs SKIP mismatch.
+                    'Check mbedtls_calloc overallocation',
+                ],
                 # Following tests depend on AES_C/DES_C but are not about
                 # them really, just need to know some error code is there.
                 'test_suite_error': [
@@ -282,7 +293,7 @@
                 'test_suite_pkparse': [
                     'Key ASN1 (Encrypted key PKCS12, trailing garbage data)',
                     'Key ASN1 (Encrypted key PKCS5, trailing garbage data)',
-                    re.compile(r'Parse RSA Key .*\(PKCS#8 encrypted .*\)'),
+                    re.compile(r'Parse (RSA|EC) Key .*\(.* ([Ee]ncrypted|password).*\)'),
                 ],
             }
         }
@@ -297,6 +308,12 @@
                 'ecdsa', 'ecdh', 'ecjpake',
             ],
             'ignored_tests': {
+                'test_suite_platform': [
+                    # Incompatible with sanitizers (e.g. ASan). If the driver
+                    # component uses a sanitizer but the reference component
+                    # doesn't, we have a PASS vs SKIP mismatch.
+                    'Check mbedtls_calloc overallocation',
+                ],
                 # This test wants a legacy function that takes f_rng, p_rng
                 # arguments, and uses legacy ECDSA for that. The test is
                 # really about the wrapper around the PSA RNG, not ECDSA.
@@ -330,6 +347,12 @@
                 'ecp', 'ecdsa', 'ecdh', 'ecjpake',
             ],
             'ignored_tests': {
+                'test_suite_platform': [
+                    # Incompatible with sanitizers (e.g. ASan). If the driver
+                    # component uses a sanitizer but the reference component
+                    # doesn't, we have a PASS vs SKIP mismatch.
+                    'Check mbedtls_calloc overallocation',
+                ],
                 # See ecp_light_only
                 'test_suite_random': [
                     'PSA classic wrapper: ECDSA signature (SECP256R1)',
@@ -363,6 +386,12 @@
                 'bignum.generated', 'bignum.misc',
             ],
             'ignored_tests': {
+                'test_suite_platform': [
+                    # Incompatible with sanitizers (e.g. ASan). If the driver
+                    # component uses a sanitizer but the reference component
+                    # doesn't, we have a PASS vs SKIP mismatch.
+                    'Check mbedtls_calloc overallocation',
+                ],
                 # See ecp_light_only
                 'test_suite_random': [
                     'PSA classic wrapper: ECDSA signature (SECP256R1)',
@@ -400,6 +429,12 @@
                 'bignum.generated', 'bignum.misc',
             ],
             'ignored_tests': {
+                'test_suite_platform': [
+                    # Incompatible with sanitizers (e.g. ASan). If the driver
+                    # component uses a sanitizer but the reference component
+                    # doesn't, we have a PASS vs SKIP mismatch.
+                    'Check mbedtls_calloc overallocation',
+                ],
                 # See ecp_light_only
                 'test_suite_random': [
                     'PSA classic wrapper: ECDSA signature (SECP256R1)',
@@ -431,7 +466,14 @@
             'component_ref': 'test_psa_crypto_config_reference_ffdh',
             'component_driver': 'test_psa_crypto_config_accel_ffdh',
             'ignored_suites': ['dhm'],
-            'ignored_tests': {}
+            'ignored_tests': {
+                'test_suite_platform': [
+                    # Incompatible with sanitizers (e.g. ASan). If the driver
+                    # component uses a sanitizer but the reference component
+                    # doesn't, we have a PASS vs SKIP mismatch.
+                    'Check mbedtls_calloc overallocation',
+                ],
+            }
         }
     },
     'analyze_driver_vs_reference_tfm_config': {
@@ -447,6 +489,12 @@
                 'bignum.generated', 'bignum.misc',
             ],
             'ignored_tests': {
+                'test_suite_platform': [
+                    # Incompatible with sanitizers (e.g. ASan). If the driver
+                    # component uses a sanitizer but the reference component
+                    # doesn't, we have a PASS vs SKIP mismatch.
+                    'Check mbedtls_calloc overallocation',
+                ],
                 # See ecp_light_only
                 'test_suite_random': [
                     'PSA classic wrapper: ECDSA signature (SECP256R1)',
@@ -493,10 +541,31 @@
 
         KNOWN_TASKS['analyze_coverage']['args']['full_coverage'] = options.full_coverage
 
+        # If the outcome file exists, parse it once and share the result
+        # among tasks to improve performance.
+        # Otherwise, it will be generated by execute_reference_driver_tests.
+        if not os.path.exists(options.outcomes):
+            if len(tasks_list) > 1:
+                sys.stderr.write("mutiple tasks found, please provide a valid outcomes file.\n")
+                sys.exit(2)
+
+            task_name = tasks_list[0]
+            task = KNOWN_TASKS[task_name]
+            if task['test_function'] != do_analyze_driver_vs_reference: # pylint: disable=comparison-with-callable
+                sys.stderr.write("please provide valid outcomes file for {}.\n".format(task_name))
+                sys.exit(2)
+
+            execute_reference_driver_tests(main_results,
+                                           task['args']['component_ref'],
+                                           task['args']['component_driver'],
+                                           options.outcomes)
+
+        outcomes = read_outcome_file(options.outcomes)
+
         for task in tasks_list:
             test_function = KNOWN_TASKS[task]['test_function']
             test_args = KNOWN_TASKS[task]['args']
-            test_function(main_results, options.outcomes, test_args)
+            test_function(main_results, outcomes, test_args)
 
         main_results.info("Overall results: {} warnings and {} errors",
                           main_results.warning_count, main_results.error_count)
diff --git a/tests/src/threading_helpers.c b/tests/src/threading_helpers.c
index 6f405b0..5fbf65b 100644
--- a/tests/src/threading_helpers.c
+++ b/tests/src/threading_helpers.c
@@ -58,15 +58,15 @@
  * indicate the exact location of the problematic call. To locate the error,
  * use a debugger and set a breakpoint on mbedtls_test_mutex_usage_error().
  */
-enum value_of_mutex_is_valid_field {
-    /* Potential values for the is_valid field of mbedtls_threading_mutex_t.
+enum value_of_mutex_state_field {
+    /* Potential values for the state field of mbedtls_threading_mutex_t.
      * Note that MUTEX_FREED must be 0 and MUTEX_IDLE must be 1 for
      * compatibility with threading_mutex_init_pthread() and
      * threading_mutex_free_pthread(). MUTEX_LOCKED could be any nonzero
      * value. */
-    MUTEX_FREED = 0, //!< Set by threading_mutex_free_pthread
-    MUTEX_IDLE = 1, //!< Set by threading_mutex_init_pthread and by our unlock
-    MUTEX_LOCKED = 2, //!< Set by our lock
+    MUTEX_FREED = 0, //! < Set by mbedtls_test_wrap_mutex_free
+    MUTEX_IDLE = 1, //! < Set by mbedtls_test_wrap_mutex_init and by mbedtls_test_wrap_mutex_unlock
+    MUTEX_LOCKED = 2, //! < Set by mbedtls_test_wrap_mutex_lock
 };
 
 typedef struct {
@@ -77,10 +77,30 @@
 } mutex_functions_t;
 static mutex_functions_t mutex_functions;
 
-/** The total number of calls to mbedtls_mutex_init(), minus the total number
- * of calls to mbedtls_mutex_free().
+/**
+ *  The mutex used to guard live_mutexes below and access to the status variable
+ *  in every mbedtls_threading_mutex_t.
+ *  Note that we are not reporting any errors when locking and unlocking this
+ *  mutex. This is for a couple of reasons:
  *
- * Reset to 0 after each test case.
+ *  1. We have no real way of reporting any errors with this mutex - we cannot
+ *  report it back to the caller, as the failure was not that of the mutex
+ *  passed in. We could fail the test, but again this would indicate a problem
+ *  with the test code that did not exist.
+ *
+ *  2. Any failure to lock is unlikely to be intermittent, and will thus not
+ *  give false test results - the overall result would be to turn off the
+ *  testing. This is not a situation that is likely to happen with normal
+ *  testing and we still have TSan to fall back on should this happen.
+ */
+mbedtls_threading_mutex_t mbedtls_test_mutex_mutex;
+
+/**
+ *  The total number of calls to mbedtls_mutex_init(), minus the total number
+ *  of calls to mbedtls_mutex_free().
+ *
+ *  Do not read or write without holding mbedtls_test_mutex_mutex (above). Reset
+ *  to 0 after each test case.
  */
 static int live_mutexes;
 
@@ -88,6 +108,7 @@
                                            const char *msg)
 {
     (void) mutex;
+
     if (mbedtls_test_info.mutex_usage_error == NULL) {
         mbedtls_test_info.mutex_usage_error = msg;
     }
@@ -101,76 +122,92 @@
 static void mbedtls_test_wrap_mutex_init(mbedtls_threading_mutex_t *mutex)
 {
     mutex_functions.init(mutex);
-    if (mutex->is_valid) {
+
+    if (mutex_functions.lock(&mbedtls_test_mutex_mutex) == 0) {
+        mutex->state = MUTEX_IDLE;
         ++live_mutexes;
+
+        mutex_functions.unlock(&mbedtls_test_mutex_mutex);
     }
 }
 
 static void mbedtls_test_wrap_mutex_free(mbedtls_threading_mutex_t *mutex)
 {
-    switch (mutex->is_valid) {
-        case MUTEX_FREED:
-            mbedtls_test_mutex_usage_error(mutex, "free without init or double free");
-            break;
-        case MUTEX_IDLE:
-            /* Do nothing. The underlying free function will reset is_valid
-             * to 0. */
-            break;
-        case MUTEX_LOCKED:
-            mbedtls_test_mutex_usage_error(mutex, "free without unlock");
-            break;
-        default:
-            mbedtls_test_mutex_usage_error(mutex, "corrupted state");
-            break;
-    }
-    if (mutex->is_valid) {
-        --live_mutexes;
+    if (mutex_functions.lock(&mbedtls_test_mutex_mutex) == 0) {
+
+        switch (mutex->state) {
+            case MUTEX_FREED:
+                mbedtls_test_mutex_usage_error(mutex, "free without init or double free");
+                break;
+            case MUTEX_IDLE:
+                mutex->state = MUTEX_FREED;
+                --live_mutexes;
+                break;
+            case MUTEX_LOCKED:
+                mbedtls_test_mutex_usage_error(mutex, "free without unlock");
+                break;
+            default:
+                mbedtls_test_mutex_usage_error(mutex, "corrupted state");
+                break;
+        }
+
+        mutex_functions.unlock(&mbedtls_test_mutex_mutex);
     }
     mutex_functions.free(mutex);
 }
 
 static int mbedtls_test_wrap_mutex_lock(mbedtls_threading_mutex_t *mutex)
 {
+    /* Lock the passed in mutex first, so that the only way to change the state
+     * is to hold the passed in and internal mutex - otherwise we create a race
+     * condition. */
     int ret = mutex_functions.lock(mutex);
-    switch (mutex->is_valid) {
-        case MUTEX_FREED:
-            mbedtls_test_mutex_usage_error(mutex, "lock without init");
-            break;
-        case MUTEX_IDLE:
-            if (ret == 0) {
-                mutex->is_valid = 2;
-            }
-            break;
-        case MUTEX_LOCKED:
-            mbedtls_test_mutex_usage_error(mutex, "double lock");
-            break;
-        default:
-            mbedtls_test_mutex_usage_error(mutex, "corrupted state");
-            break;
+    if (mutex_functions.lock(&mbedtls_test_mutex_mutex) == 0) {
+        switch (mutex->state) {
+            case MUTEX_FREED:
+                mbedtls_test_mutex_usage_error(mutex, "lock without init");
+                break;
+            case MUTEX_IDLE:
+                if (ret == 0) {
+                    mutex->state = MUTEX_LOCKED;
+                }
+                break;
+            case MUTEX_LOCKED:
+                mbedtls_test_mutex_usage_error(mutex, "double lock");
+                break;
+            default:
+                mbedtls_test_mutex_usage_error(mutex, "corrupted state");
+                break;
+        }
+
+        mutex_functions.unlock(&mbedtls_test_mutex_mutex);
     }
     return ret;
 }
 
 static int mbedtls_test_wrap_mutex_unlock(mbedtls_threading_mutex_t *mutex)
 {
-    int ret = mutex_functions.unlock(mutex);
-    switch (mutex->is_valid) {
-        case MUTEX_FREED:
-            mbedtls_test_mutex_usage_error(mutex, "unlock without init");
-            break;
-        case MUTEX_IDLE:
-            mbedtls_test_mutex_usage_error(mutex, "unlock without lock");
-            break;
-        case MUTEX_LOCKED:
-            if (ret == 0) {
-                mutex->is_valid = MUTEX_IDLE;
-            }
-            break;
-        default:
-            mbedtls_test_mutex_usage_error(mutex, "corrupted state");
-            break;
+    /* Lock the internal mutex first and change state, so that the only way to
+     * change the state is to hold the passed in and internal mutex - otherwise
+     * we create a race condition. */
+    if (mutex_functions.lock(&mbedtls_test_mutex_mutex) == 0) {
+        switch (mutex->state) {
+            case MUTEX_FREED:
+                mbedtls_test_mutex_usage_error(mutex, "unlock without init");
+                break;
+            case MUTEX_IDLE:
+                mbedtls_test_mutex_usage_error(mutex, "unlock without lock");
+                break;
+            case MUTEX_LOCKED:
+                mutex->state = MUTEX_IDLE;
+                break;
+            default:
+                mbedtls_test_mutex_usage_error(mutex, "corrupted state");
+                break;
+        }
+        mutex_functions.unlock(&mbedtls_test_mutex_mutex);
     }
-    return ret;
+    return mutex_functions.unlock(mutex);
 }
 
 void mbedtls_test_mutex_usage_init(void)
@@ -183,6 +220,8 @@
     mbedtls_mutex_free = &mbedtls_test_wrap_mutex_free;
     mbedtls_mutex_lock = &mbedtls_test_wrap_mutex_lock;
     mbedtls_mutex_unlock = &mbedtls_test_wrap_mutex_unlock;
+
+    mutex_functions.init(&mbedtls_test_mutex_mutex);
 }
 
 void mbedtls_test_mutex_usage_check(void)
@@ -207,4 +246,14 @@
     mbedtls_test_info.mutex_usage_error = NULL;
 }
 
+void mbedtls_test_mutex_usage_end(void)
+{
+    mbedtls_mutex_init = mutex_functions.init;
+    mbedtls_mutex_free = mutex_functions.free;
+    mbedtls_mutex_lock = mutex_functions.lock;
+    mbedtls_mutex_unlock = mutex_functions.unlock;
+
+    mutex_functions.free(&mbedtls_test_mutex_mutex);
+}
+
 #endif /* MBEDTLS_TEST_MUTEX_USAGE */
diff --git a/tests/ssl-opt.sh b/tests/ssl-opt.sh
index 42f9f5e..4762285 100755
--- a/tests/ssl-opt.sh
+++ b/tests/ssl-opt.sh
@@ -358,9 +358,18 @@
 
 # Space-separated list of ciphersuites supported by this build of
 # Mbed TLS.
-P_CIPHERSUITES=" $($P_CLI --help 2>/dev/null |
-                   grep 'TLS-\|TLS1-3' |
-                   tr -s ' \n' ' ')"
+P_CIPHERSUITES=""
+if [ "$LIST_TESTS" -eq 0 ]; then
+    P_CIPHERSUITES=" $($P_CLI help_ciphersuites 2>/dev/null |
+                       grep 'TLS-\|TLS1-3' |
+                       tr -s ' \n' ' ')"
+
+    if [ -z "${P_CIPHERSUITES# }" ]; then
+        echo >&2 "$0: fatal error: no cipher suites found!"
+        exit 125
+    fi
+fi
+
 requires_ciphersuite_enabled() {
     case $P_CIPHERSUITES in
         *" $1 "*) :;;
@@ -2332,7 +2341,6 @@
 requires_config_enabled MBEDTLS_USE_PSA_CRYPTO
 requires_config_enabled MBEDTLS_X509_CRT_PARSE_C
 requires_hash_alg SHA_256
-requires_config_enabled MBEDTLS_CCM_C
 run_test    "Opaque key for server authentication: invalid alg: ECDHE-ECDSA with ecdh" \
             "$P_SRV key_opaque=1 crt_file=data_files/server5.crt \
              key_file=data_files/server5.key key_opaque_algs=ecdh,none \
@@ -2386,7 +2394,6 @@
 requires_config_enabled MBEDTLS_USE_PSA_CRYPTO
 requires_config_enabled MBEDTLS_X509_CRT_PARSE_C
 requires_hash_alg SHA_384
-requires_config_enabled MBEDTLS_CCM_C
 requires_config_disabled MBEDTLS_X509_REMOVE_INFO
 run_test    "Opaque keys for server authentication: EC + RSA, force ECDHE-ECDSA" \
             "$P_SRV key_opaque=1 crt_file=data_files/server5.crt \
@@ -2566,7 +2573,6 @@
 requires_config_enabled MBEDTLS_X509_CRT_PARSE_C
 requires_config_enabled MBEDTLS_RSA_C
 requires_hash_alg SHA_384
-requires_config_enabled MBEDTLS_GCM_C
 requires_config_disabled MBEDTLS_X509_REMOVE_INFO
 run_test    "Opaque keys for server authentication: EC + RSA, force DHE-RSA" \
             "$P_SRV auth_mode=required key_opaque=1 crt_file=data_files/server5.crt \
@@ -9115,8 +9121,6 @@
 
 # Tests for ECC extensions (rfc 4492)
 
-requires_config_enabled MBEDTLS_AES_C
-requires_config_enabled MBEDTLS_CIPHER_MODE_CBC
 requires_hash_alg SHA_256
 requires_config_enabled MBEDTLS_KEY_EXCHANGE_RSA_ENABLED
 run_test    "Force a non ECC ciphersuite in the client side" \
@@ -9128,8 +9132,6 @@
             -S "found supported elliptic curves extension" \
             -S "found supported point formats extension"
 
-requires_config_enabled MBEDTLS_AES_C
-requires_config_enabled MBEDTLS_CIPHER_MODE_CBC
 requires_hash_alg SHA_256
 requires_config_enabled MBEDTLS_KEY_EXCHANGE_RSA_ENABLED
 run_test    "Force a non ECC ciphersuite in the server side" \
@@ -9139,8 +9141,6 @@
             -C "found supported_point_formats extension" \
             -S "server hello, supported_point_formats extension"
 
-requires_config_enabled MBEDTLS_AES_C
-requires_config_enabled MBEDTLS_CIPHER_MODE_CBC
 requires_hash_alg SHA_256
 run_test    "Force an ECC ciphersuite in the client side" \
             "$P_SRV debug_level=3" \
@@ -9151,8 +9151,6 @@
             -s "found supported elliptic curves extension" \
             -s "found supported point formats extension"
 
-requires_config_enabled MBEDTLS_AES_C
-requires_config_enabled MBEDTLS_CIPHER_MODE_CBC
 requires_hash_alg SHA_256
 run_test    "Force an ECC ciphersuite in the server side" \
             "$P_SRV debug_level=3 force_ciphersuite=TLS-ECDHE-ECDSA-WITH-AES-128-CBC-SHA256" \
@@ -9677,8 +9675,6 @@
 requires_config_enabled MBEDTLS_SSL_PROTO_DTLS
 requires_config_enabled MBEDTLS_RSA_C
 requires_hash_alg SHA_256
-requires_config_enabled MBEDTLS_AES_C
-requires_config_enabled MBEDTLS_GCM_C
 requires_max_content_len 2048
 run_test    "DTLS fragmenting: both (MTU=512)" \
             -p "$P_PXY mtu=512" \
@@ -9707,8 +9703,6 @@
 not_with_valgrind
 requires_config_enabled MBEDTLS_SSL_PROTO_DTLS
 requires_config_enabled MBEDTLS_RSA_C
-requires_config_enabled MBEDTLS_AES_C
-requires_config_enabled MBEDTLS_GCM_C
 requires_max_content_len 2048
 run_test    "DTLS fragmenting: proxy MTU: auto-reduction (not valgrind)" \
             -p "$P_PXY mtu=508" \
@@ -9730,8 +9724,6 @@
 only_with_valgrind
 requires_config_enabled MBEDTLS_SSL_PROTO_DTLS
 requires_config_enabled MBEDTLS_RSA_C
-requires_config_enabled MBEDTLS_AES_C
-requires_config_enabled MBEDTLS_GCM_C
 requires_max_content_len 2048
 run_test    "DTLS fragmenting: proxy MTU: auto-reduction (with valgrind)" \
             -p "$P_PXY mtu=508" \
@@ -9782,8 +9774,6 @@
 not_with_valgrind # spurious autoreduction due to timeout
 requires_config_enabled MBEDTLS_SSL_PROTO_DTLS
 requires_config_enabled MBEDTLS_RSA_C
-requires_config_enabled MBEDTLS_AES_C
-requires_config_enabled MBEDTLS_GCM_C
 requires_max_content_len 2048
 run_test    "DTLS fragmenting: proxy MTU, simple handshake (MTU=512)" \
             -p "$P_PXY mtu=512" \
@@ -9831,8 +9821,6 @@
 not_with_valgrind # spurious autoreduction due to timeout
 requires_config_enabled MBEDTLS_SSL_PROTO_DTLS
 requires_config_enabled MBEDTLS_RSA_C
-requires_config_enabled MBEDTLS_AES_C
-requires_config_enabled MBEDTLS_GCM_C
 requires_max_content_len 2048
 run_test    "DTLS fragmenting: proxy MTU, simple handshake, nbio (MTU=512)" \
             -p "$P_PXY mtu=512" \
@@ -9866,8 +9854,6 @@
 not_with_valgrind # spurious autoreduction due to timeout
 requires_config_enabled MBEDTLS_SSL_PROTO_DTLS
 requires_config_enabled MBEDTLS_RSA_C
-requires_config_enabled MBEDTLS_AES_C
-requires_config_enabled MBEDTLS_GCM_C
 requires_max_content_len 2048
 run_test    "DTLS fragmenting: proxy MTU, resumed handshake" \
             -p "$P_PXY mtu=1450" \
@@ -9895,7 +9881,6 @@
 requires_config_enabled MBEDTLS_RSA_C
 requires_hash_alg SHA_256
 requires_config_enabled MBEDTLS_SSL_RENEGOTIATION
-requires_config_enabled MBEDTLS_CHACHAPOLY_C
 requires_max_content_len 2048
 run_test    "DTLS fragmenting: proxy MTU, ChachaPoly renego" \
             -p "$P_PXY mtu=512" \
@@ -9909,7 +9894,7 @@
              crt_file=data_files/server8_int-ca2.crt \
              key_file=data_files/server8.key \
              exchanges=2 renegotiation=1 renegotiate=1 \
-             force_ciphersuite=TLS-ECDHE-ECDSA-WITH-AES-128-GCM-SHA256 \
+             force_ciphersuite=TLS-ECDHE-ECDSA-WITH-CHACHA20-POLY1305-SHA256 \
              hs_timeout=10000-60000 \
              mtu=512" \
             0 \
@@ -9925,8 +9910,6 @@
 requires_config_enabled MBEDTLS_RSA_C
 requires_hash_alg SHA_256
 requires_config_enabled MBEDTLS_SSL_RENEGOTIATION
-requires_config_enabled MBEDTLS_AES_C
-requires_config_enabled MBEDTLS_GCM_C
 requires_max_content_len 2048
 run_test    "DTLS fragmenting: proxy MTU, AES-GCM renego" \
             -p "$P_PXY mtu=512" \
@@ -9956,8 +9939,6 @@
 requires_config_enabled MBEDTLS_RSA_C
 requires_hash_alg SHA_256
 requires_config_enabled MBEDTLS_SSL_RENEGOTIATION
-requires_config_enabled MBEDTLS_AES_C
-requires_config_enabled MBEDTLS_CCM_C
 requires_max_content_len 2048
 run_test    "DTLS fragmenting: proxy MTU, AES-CCM renego" \
             -p "$P_PXY mtu=1024" \
@@ -9987,8 +9968,6 @@
 requires_config_enabled MBEDTLS_RSA_C
 requires_hash_alg SHA_256
 requires_config_enabled MBEDTLS_SSL_RENEGOTIATION
-requires_config_enabled MBEDTLS_AES_C
-requires_config_enabled MBEDTLS_CIPHER_MODE_CBC
 requires_config_enabled MBEDTLS_SSL_ENCRYPT_THEN_MAC
 requires_max_content_len 2048
 run_test    "DTLS fragmenting: proxy MTU, AES-CBC EtM renego" \
@@ -10019,8 +9998,6 @@
 requires_config_enabled MBEDTLS_RSA_C
 requires_hash_alg SHA_256
 requires_config_enabled MBEDTLS_SSL_RENEGOTIATION
-requires_config_enabled MBEDTLS_AES_C
-requires_config_enabled MBEDTLS_CIPHER_MODE_CBC
 requires_max_content_len 2048
 run_test    "DTLS fragmenting: proxy MTU, AES-CBC non-EtM renego" \
             -p "$P_PXY mtu=1024" \
@@ -10046,8 +10023,6 @@
 # Forcing ciphersuite for this test to fit the MTU of 512 with full config.
 requires_config_enabled MBEDTLS_SSL_PROTO_DTLS
 requires_config_enabled MBEDTLS_RSA_C
-requires_config_enabled MBEDTLS_AES_C
-requires_config_enabled MBEDTLS_GCM_C
 client_needs_more_time 2
 requires_max_content_len 2048
 run_test    "DTLS fragmenting: proxy MTU + 3d" \
@@ -10069,8 +10044,6 @@
 # Forcing ciphersuite for this test to fit the MTU of 512 with full config.
 requires_config_enabled MBEDTLS_SSL_PROTO_DTLS
 requires_config_enabled MBEDTLS_RSA_C
-requires_config_enabled MBEDTLS_AES_C
-requires_config_enabled MBEDTLS_GCM_C
 client_needs_more_time 2
 requires_max_content_len 2048
 run_test    "DTLS fragmenting: proxy MTU + 3d, nbio" \
diff --git a/tests/suites/host_test.function b/tests/suites/host_test.function
index d8ff49e..cc28697 100644
--- a/tests/suites/host_test.function
+++ b/tests/suites/host_test.function
@@ -772,6 +772,10 @@
     mbedtls_fprintf(stdout, " (%u / %u tests (%u skipped))\n",
                     total_tests - total_errors, total_tests, total_skipped);
 
+#if defined(MBEDTLS_TEST_MUTEX_USAGE)
+    mbedtls_test_mutex_usage_end();
+#endif
+
 #if defined(MBEDTLS_MEMORY_BUFFER_ALLOC_C) && \
     !defined(TEST_SUITE_MEMORY_BUFFER_ALLOC)
 #if defined(MBEDTLS_MEMORY_DEBUG)
diff --git a/tests/suites/test_suite_pkparse.data b/tests/suites/test_suite_pkparse.data
index f82dcb5..7173511 100644
--- a/tests/suites/test_suite_pkparse.data
+++ b/tests/suites/test_suite_pkparse.data
@@ -1,77 +1,77 @@
 Parse RSA Key #1 (No password when required)
-depends_on:MBEDTLS_HAS_MD5_VIA_LOWLEVEL_OR_PSA :MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC:MBEDTLS_AES_C
+depends_on:MBEDTLS_MD_CAN_MD5:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC:MBEDTLS_AES_C
 pk_parse_keyfile_rsa:"data_files/test-ca.key":"NULL":MBEDTLS_ERR_PK_PASSWORD_REQUIRED
 
 Parse RSA Key #2 (Correct password)
-depends_on:MBEDTLS_HAS_MD5_VIA_LOWLEVEL_OR_PSA :MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC:MBEDTLS_AES_C
+depends_on:MBEDTLS_MD_CAN_MD5:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC:MBEDTLS_AES_C
 pk_parse_keyfile_rsa:"data_files/test-ca.key":"PolarSSLTest":0
 
 Parse RSA Key #3 (Wrong password)
-depends_on:MBEDTLS_HAS_MD5_VIA_LOWLEVEL_OR_PSA :MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC:MBEDTLS_AES_C
+depends_on:MBEDTLS_MD_CAN_MD5:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC:MBEDTLS_AES_C
 pk_parse_keyfile_rsa:"data_files/test-ca.key":"PolarSSLWRONG":MBEDTLS_ERR_PK_PASSWORD_MISMATCH
 
 Parse RSA Key #4 (DES Encrypted)
-depends_on:MBEDTLS_HAS_MD5_VIA_LOWLEVEL_OR_PSA :MBEDTLS_DES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC
+depends_on:MBEDTLS_MD_CAN_MD5:MBEDTLS_DES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC
 pk_parse_keyfile_rsa:"data_files/rsa_pkcs1_1024_des.pem":"testkey":0
 
 Parse RSA Key #5 (3DES Encrypted)
-depends_on:MBEDTLS_HAS_MD5_VIA_LOWLEVEL_OR_PSA :MBEDTLS_DES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC
+depends_on:MBEDTLS_MD_CAN_MD5:MBEDTLS_DES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC
 pk_parse_keyfile_rsa:"data_files/rsa_pkcs1_1024_3des.pem":"testkey":0
 
 Parse RSA Key #6 (AES-128 Encrypted)
-depends_on:MBEDTLS_HAS_MD5_VIA_LOWLEVEL_OR_PSA :MBEDTLS_AES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC
+depends_on:MBEDTLS_MD_CAN_MD5:MBEDTLS_AES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC
 pk_parse_keyfile_rsa:"data_files/rsa_pkcs1_1024_aes128.pem":"testkey":0
 
 Parse RSA Key #7 (AES-192 Encrypted)
-depends_on:MBEDTLS_HAS_MD5_VIA_LOWLEVEL_OR_PSA :MBEDTLS_AES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC:!MBEDTLS_AES_ONLY_128_BIT_KEY_LENGTH
+depends_on:MBEDTLS_MD_CAN_MD5:MBEDTLS_AES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC:!MBEDTLS_AES_ONLY_128_BIT_KEY_LENGTH
 pk_parse_keyfile_rsa:"data_files/rsa_pkcs1_1024_aes192.pem":"testkey":0
 
 Parse RSA Key #8 (AES-256 Encrypted)
-depends_on:MBEDTLS_HAS_MD5_VIA_LOWLEVEL_OR_PSA :MBEDTLS_AES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC:!MBEDTLS_AES_ONLY_128_BIT_KEY_LENGTH
+depends_on:MBEDTLS_MD_CAN_MD5:MBEDTLS_AES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC:!MBEDTLS_AES_ONLY_128_BIT_KEY_LENGTH
 pk_parse_keyfile_rsa:"data_files/rsa_pkcs1_1024_aes256.pem":"testkey":0
 
 Parse RSA Key #9 (2048-bit, DES Encrypted)
-depends_on:MBEDTLS_HAS_MD5_VIA_LOWLEVEL_OR_PSA :MBEDTLS_DES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC
+depends_on:MBEDTLS_MD_CAN_MD5:MBEDTLS_DES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC
 pk_parse_keyfile_rsa:"data_files/rsa_pkcs1_2048_des.pem":"testkey":0
 
 Parse RSA Key #10 (2048-bit, 3DES Encrypted)
-depends_on:MBEDTLS_HAS_MD5_VIA_LOWLEVEL_OR_PSA :MBEDTLS_DES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC
+depends_on:MBEDTLS_MD_CAN_MD5:MBEDTLS_DES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC
 pk_parse_keyfile_rsa:"data_files/rsa_pkcs1_2048_3des.pem":"testkey":0
 
 Parse RSA Key #11 (2048-bit, AES-128 Encrypted)
-depends_on:MBEDTLS_HAS_MD5_VIA_LOWLEVEL_OR_PSA :MBEDTLS_AES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC
+depends_on:MBEDTLS_MD_CAN_MD5:MBEDTLS_AES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC
 pk_parse_keyfile_rsa:"data_files/rsa_pkcs1_2048_aes128.pem":"testkey":0
 
 Parse RSA Key #12 (2048-bit, AES-192 Encrypted)
-depends_on:MBEDTLS_HAS_MD5_VIA_LOWLEVEL_OR_PSA :MBEDTLS_AES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC:!MBEDTLS_AES_ONLY_128_BIT_KEY_LENGTH
+depends_on:MBEDTLS_MD_CAN_MD5:MBEDTLS_AES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC:!MBEDTLS_AES_ONLY_128_BIT_KEY_LENGTH
 pk_parse_keyfile_rsa:"data_files/rsa_pkcs1_2048_aes192.pem":"testkey":0
 
 Parse RSA Key #13 (2048-bit, AES-256 Encrypted)
-depends_on:MBEDTLS_HAS_MD5_VIA_LOWLEVEL_OR_PSA :MBEDTLS_AES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC:!MBEDTLS_AES_ONLY_128_BIT_KEY_LENGTH
+depends_on:MBEDTLS_MD_CAN_MD5:MBEDTLS_AES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC:!MBEDTLS_AES_ONLY_128_BIT_KEY_LENGTH
 pk_parse_keyfile_rsa:"data_files/rsa_pkcs1_2048_aes256.pem":"testkey":0
 
 Parse RSA Key #14 (4096-bit, DES Encrypted)
-depends_on:MBEDTLS_HAS_MD5_VIA_LOWLEVEL_OR_PSA :MBEDTLS_DES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC
+depends_on:MBEDTLS_MD_CAN_MD5:MBEDTLS_DES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC
 pk_parse_keyfile_rsa:"data_files/rsa_pkcs1_4096_des.pem":"testkey":0
 
 Parse RSA Key #15 (4096-bit, 3DES Encrypted)
-depends_on:MBEDTLS_HAS_MD5_VIA_LOWLEVEL_OR_PSA :MBEDTLS_DES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC
+depends_on:MBEDTLS_MD_CAN_MD5:MBEDTLS_DES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC
 pk_parse_keyfile_rsa:"data_files/rsa_pkcs1_4096_3des.pem":"testkey":0
 
 Parse RSA Key #16 (4096-bit, AES-128 Encrypted)
-depends_on:MBEDTLS_HAS_MD5_VIA_LOWLEVEL_OR_PSA :MBEDTLS_AES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC
+depends_on:MBEDTLS_MD_CAN_MD5:MBEDTLS_AES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC
 pk_parse_keyfile_rsa:"data_files/rsa_pkcs1_4096_aes128.pem":"testkey":0
 
 Parse RSA Key #17 (4096-bit, AES-192 Encrypted)
-depends_on:MBEDTLS_HAS_MD5_VIA_LOWLEVEL_OR_PSA :MBEDTLS_AES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC:!MBEDTLS_AES_ONLY_128_BIT_KEY_LENGTH
+depends_on:MBEDTLS_MD_CAN_MD5:MBEDTLS_AES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC:!MBEDTLS_AES_ONLY_128_BIT_KEY_LENGTH
 pk_parse_keyfile_rsa:"data_files/rsa_pkcs1_4096_aes192.pem":"testkey":0
 
 Parse RSA Key #18 (4096-bit, AES-256 Encrypted)
-depends_on:MBEDTLS_HAS_MD5_VIA_LOWLEVEL_OR_PSA :MBEDTLS_AES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC:!MBEDTLS_AES_ONLY_128_BIT_KEY_LENGTH
+depends_on:MBEDTLS_MD_CAN_MD5:MBEDTLS_AES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_CIPHER_MODE_CBC:!MBEDTLS_AES_ONLY_128_BIT_KEY_LENGTH
 pk_parse_keyfile_rsa:"data_files/rsa_pkcs1_4096_aes256.pem":"testkey":0
 
 Parse RSA Key #19 (PKCS#8 wrapped)
-depends_on:MBEDTLS_HAS_MD5_VIA_LOWLEVEL_OR_PSA :MBEDTLS_PEM_PARSE_C
+depends_on:MBEDTLS_MD_CAN_MD5:MBEDTLS_PEM_PARSE_C
 pk_parse_keyfile_rsa:"data_files/format_gen.key":"":0
 
 Parse RSA Key #20 (PKCS#8 encrypted SHA1-3DES)
@@ -1003,7 +1003,7 @@
 pk_parse_keyfile_ec:"data_files/ec_prv.sec1.comp.pem":"NULL":0
 
 Parse EC Key #3 (SEC1 PEM encrypted)
-depends_on:MBEDTLS_DES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_ECP_HAVE_SECP192R1:MBEDTLS_CIPHER_MODE_CBC:MBEDTLS_HAS_MD5_VIA_LOWLEVEL_OR_PSA
+depends_on:MBEDTLS_DES_C:MBEDTLS_PEM_PARSE_C:MBEDTLS_ECP_HAVE_SECP192R1:MBEDTLS_CIPHER_MODE_CBC:MBEDTLS_MD_CAN_MD5
 pk_parse_keyfile_ec:"data_files/ec_prv.sec1.pw.pem":"polar":0
 
 Parse EC Key #4 (PKCS8 DER)
diff --git a/tests/suites/test_suite_pkparse.function b/tests/suites/test_suite_pkparse.function
index 64a3175..d416b87 100644
--- a/tests/suites/test_suite_pkparse.function
+++ b/tests/suites/test_suite_pkparse.function
@@ -34,13 +34,13 @@
     res = mbedtls_pk_parse_keyfile(&ctx, key_file, pwd,
                                    mbedtls_test_rnd_std_rand, NULL);
 
-    TEST_ASSERT(res == result);
+    TEST_EQUAL(res, result);
 
     if (res == 0) {
         mbedtls_rsa_context *rsa;
         TEST_ASSERT(mbedtls_pk_can_do(&ctx, MBEDTLS_PK_RSA));
         rsa = mbedtls_pk_rsa(ctx);
-        TEST_ASSERT(mbedtls_rsa_check_privkey(rsa) == 0);
+        TEST_EQUAL(mbedtls_rsa_check_privkey(rsa), 0);
     }
 
 exit:
@@ -61,13 +61,13 @@
 
     res = mbedtls_pk_parse_public_keyfile(&ctx, key_file);
 
-    TEST_ASSERT(res == result);
+    TEST_EQUAL(res, result);
 
     if (res == 0) {
         mbedtls_rsa_context *rsa;
         TEST_ASSERT(mbedtls_pk_can_do(&ctx, MBEDTLS_PK_RSA));
         rsa = mbedtls_pk_rsa(ctx);
-        TEST_ASSERT(mbedtls_rsa_check_pubkey(rsa) == 0);
+        TEST_EQUAL(mbedtls_rsa_check_pubkey(rsa), 0);
     }
 
 exit:
@@ -83,11 +83,11 @@
     int res;
 
     mbedtls_pk_init(&ctx);
-    USE_PSA_INIT();
+    MD_OR_USE_PSA_INIT();
 
     res = mbedtls_pk_parse_public_keyfile(&ctx, key_file);
 
-    TEST_ASSERT(res == result);
+    TEST_EQUAL(res, result);
 
     if (res == 0) {
         TEST_ASSERT(mbedtls_pk_can_do(&ctx, MBEDTLS_PK_ECKEY));
@@ -98,13 +98,13 @@
 #else
         const mbedtls_ecp_keypair *eckey;
         eckey = mbedtls_pk_ec_ro(ctx);
-        TEST_ASSERT(mbedtls_ecp_check_pubkey(&eckey->grp, &eckey->Q) == 0);
+        TEST_EQUAL(mbedtls_ecp_check_pubkey(&eckey->grp, &eckey->Q), 0);
 #endif
     }
 
 exit:
     mbedtls_pk_free(&ctx);
-    USE_PSA_DONE();
+    MD_OR_USE_PSA_DONE();
 }
 /* END_CASE */
 
@@ -115,18 +115,18 @@
     int res;
 
     mbedtls_pk_init(&ctx);
-    USE_PSA_INIT();
+    MD_OR_USE_PSA_INIT();
 
     res = mbedtls_pk_parse_keyfile(&ctx, key_file, password,
                                    mbedtls_test_rnd_std_rand, NULL);
 
-    TEST_ASSERT(res == result);
+    TEST_EQUAL(res, result);
 
     if (res == 0) {
         TEST_ASSERT(mbedtls_pk_can_do(&ctx, MBEDTLS_PK_ECKEY));
 #if defined(MBEDTLS_ECP_C)
         const mbedtls_ecp_keypair *eckey = mbedtls_pk_ec_ro(ctx);
-        TEST_ASSERT(mbedtls_ecp_check_privkey(&eckey->grp, &eckey->d) == 0);
+        TEST_EQUAL(mbedtls_ecp_check_privkey(&eckey->grp, &eckey->d), 0);
 #else
         /* PSA keys are already checked on import so nothing to do here. */
 #endif
@@ -134,7 +134,7 @@
 
 exit:
     mbedtls_pk_free(&ctx);
-    USE_PSA_DONE();
+    MD_OR_USE_PSA_DONE();
 }
 /* END_CASE */
 
diff --git a/tests/suites/test_suite_platform.data b/tests/suites/test_suite_platform.data
index 4d57450..653d254 100644
--- a/tests/suites/test_suite_platform.data
+++ b/tests/suites/test_suite_platform.data
@@ -6,4 +6,10 @@
 time_get_seconds:
 
 Check mbedtls_calloc overallocation
+# This test case exercises an integer overflow in calloc. Under Asan, with
+# a modern Clang, this triggers an ASan/MSan/TSan complaint. The complaint
+# can be avoided with e.g. ASAN_OPTIONS=allocator_may_return_null=1,
+# but this has to be set in the environment before the program starts,
+# and could hide other errors.
+depends_on:!MBEDTLS_TEST_HAVE_ASAN:!MBEDTLS_TEST_HAVE_MSAN:!MBEDTLS_TEST_HAVE_TSAN
 check_mbedtls_calloc_overallocation:SIZE_MAX/2:SIZE_MAX/2